Causes and Symptoms
Labels Canker Sores
The exact cause of canker sores is not known; however, some doctors
think that the sores develop when the person’s immune system targets
the tissues of the mouth.
There are a number of possible factors that may
trigger such a reaction:
Canker sores, particularly minor sores, usually heal without difficulty
even though they may be painful for a week or so.
Patients should, however, see their dentist or doctor if they have any
of the following symptoms, which are not normal for
ordinary canker sores:
think that the sores develop when the person’s immune system targets
the tissues of the mouth.
There are a number of possible factors that may
trigger such a reaction:
- Trauma. Canker sores sometimes develop when a person’s mouth
is irritated by poorly fitted dentures, loose wires from orthodontic
braces, a rough tooth, or accidentally biting the inside of the
mouth. Brushing too hard or using a very stiff toothbrush have
also been associated with damage to the lining of the mouth and
canker sores. - Nutritional deficiencies. People who are not getting enough
vitamin B12, iron, zinc, or folic acid in their diet are more likely
to develop canker sores. - Infection by Helicobacter pylori, the same bacterium that causes
stomach ulcers. - Stress. Researchers have noted that high-achieving people and
people with higher-than-average anxiety levels are more likely to
develop canker sores. - In women, hormonal changes during menstruation and pregnancy
are often associated with an outbreak of canker sores. - AIDS and other disorders that affect the immune system.
- Food allergies. Flavoring agents, essential oils,
benzoic acid, cinnamon, gluten, cow’s milk, coffee,
chocolate, potatoes, cheese, figs, nuts, citrus fruits,
and certain spices have all been associated with canker sores
in some people. - Sensitivity to certain chemicals found in toothpastes
and mouthwashes, particularly sodium lauryl sulfate (SLS),
a chemical added to toothpaste to thicken it
and create a lather during brushing.
Canker sores, particularly minor sores, usually heal without difficulty
even though they may be painful for a week or so.
Patients should, however, see their dentist or doctor if they have any
of the following symptoms, which are not normal for
ordinary canker sores:
- Fever, particularly fever of 101°F
(38.3°C) or higher - Headache
- Pains in the muscles and joints
- Unusually large sores
- New sores developing before old ones
heal - Sores that extend outward from the
lining of the mouth into the lips - Pain that cannot be controlled by
ordinary self-care treatments - Severe difficulty in eating or drinking
- Nausea, vomiting, or diarrhea
- Sore throat or swollen glands in the neck
- Rash on the face or body

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