Definition

Coronary artery disease, or CAD, is a condition in which a fatty substance
called plaque builds up inside the walls of the arteries that supply
the heart. The plaque begins to form when the inner layer of tissue in the
artery is damaged by smoking, diabetes, high blood pressure, personality
factors, or some other cause. When the deposit of plaque grows large
enough to narrow or block the flow of blood through the artery, the
heart muscle becomes starved for oxygen, producing angina, difficulty
breathing, or a full-blown heart attack.

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